Product Details
< bcrc (,,) / r, r : (,,) br rcb >[Common name] Sorafenib
< bcrc (,,) / r, r : (,,) br rcb >[Indications] Sorafenib has been approved to treat advanced renal cell carcinoma (the most common type of kidney cancer). In addition, various clinical trials using sorafenib to treat various other cancers are currently ongoing around the world.
< bcrc (,,) / r, r : (,,) br rcb >【Notes】
< bcrc (,,) / r, r : (,,) br rcb >It is recommended to Blood pressure should be measured weekly during the first week of sorafenib treatment. Because sorafenib can increase the risk of bleeding in patients, patients who are concurrently treated with warfarin should undergo relevant examinations regularly. Patients with a tendency of active bleeding (such as gastrointestinal bleeding) should use sorafenib with caution. It has been reported that sorafenib may cause bone marrow suppression (such as neutropenia and thrombocytopenia), so that is Patients who have previously undergone myelosuppressive therapy (including radiotherapy and chemotherapy) should be cautious when using sorafenib. Patients with active infections (including fungal infections or viral infections) should receive relevant treatment before using sorafenib. Patients who have been infected with herpes viruses such as herpes zoster, herpes simplex, or have a history of other viral infections,
< bcrc (,,) / r, r : (,,) br rcb >after chemotherapy , the infection may recur. Patients should not undergo intramuscular injection while taking sorafenib. This is mainly because sorafenib may induce thrombocytopenia, making patients prone to bleeding, bruises or hematomas.
< bcrc (,,) / r, r : (,,) br rcb >Based on the animal experimental results of sorafenib and its mechanism of action, this drug is included in the risk classification category for use during pregnancy. Therefore, Pregnant women should take contraceptive measures while taking sorafenib. If they become pregnant while taking sorafenib, doctors should clearly inform the patient of the dangers of this drug to the fetus. It is best not to breastfeed while taking sorafenib. The safety and efficacy of sorafenib in pediatric patients
< bcrc (,,) / r, r : (,,) br rcb > have not been established. Sorafenib should be used with caution in patients with liver disease, jaundice or renal disease (CrC ).
< bcrc (,,) / r, r : (,,) br rcb >【Adverse reaction】
< bcrc (,,) / r, r : (,,) br rcb >Sora Common adverse events caused by fenib include rash, diarrhea, increased blood pressure, and redness, pain, swelling, or blisters on the palms or soles of the feet. In clinical trials, the most common treatment-related adverse events were diarrhea, rash/scaling, fatigue, skin reactions of the hands and feet, alopecia, nausea, vomiting, pruritus, hypertension, and decreased appetite. In patients treated with sorafenib
< bcrc (,,) / r, r : (,,) br rcb >, the number of grade and grade adverse events accounted for the sum of total adverse events, respectively, and placebo The patients in the control group were and respectively.
< bcrc (,,) / r, r : (,,) br rcb >【Dosage】
< bcrc (,,) / r, r : (,,) br rcb >Sola Fenib is available as a red, film-coated tablet in one tablet strength. The recommended dose of sorafenib for the treatment of renal cell carcinoma is three times a day and should not be taken with food (it should be taken before or after eating). The drug manufacturer recommends that the drug be used long-term unless the efficacy of sorafenib decreases or patients cannot tolerate its toxic effects. If
< bcrc (,,) / r, r : (,,) br rcb > the patient experiences adverse drug reactions, the dose of sorafenib can be reduced to once a day or every other day.
< bcrc (,,) / r, r : (,,) br rcb >【Medication Tips】
< bcrc (,,) / r, r : (,,) br rcb >The patient is Please read the product instructions and patient instructions carefully before taking the medicine. Patients should be informed that they must use effective contraception while taking the drug and must wait at least 10 weeks after stopping the drug before trying to become pregnant. Inform patients that it is best to take the medication on an empty stomach. If the patient forgets to take the medicine, there is no need to increase the dose the next time. When patients develop rash on their hands and feet while taking the medicine, they should contact their doctor promptly for
< bcrc (,,) / r, r : (,,) br rcb > for corresponding treatment.
< bcrc (,,) / r, r : (,,) br rcb >[Storage] Store in a sealed container at ℃. Please keep the medicine out of the reach of children.
< bcrc (,,) / r, r : (,,) br rcb >【Packaging】Sheet/box
< bcrc (,,) / r, r : (,,) br rcb > [Validity period] months
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