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dd ,) dd dh , dd 【Drug name】
dd ,) dd dh , dd )
dd ,) dd dh , dd Generic name: Gefitinib tablets
dd ,) dd dh , dd )
dd ,) dd dh , dd .
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dd ,) dd dh , dd )
dd ,) dd dh , dd 【Pharmacological effects】
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dd ,) dd dh , dd )
dd ,) dd dh , dd Gefitinib is a selective inhibitor of epidermal growth factor receptor
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tyrosine kinase, an enzyme commonly expressed in Solid tumors of epithelial origin.
dd ,) dd dh , dd )
dd ,) dd dh , dd [Safety]
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Gefitinib was generally well tolerated. Most adverse events were mild and did not require treatment. The adverse event reported by more than
)
% of subjects was rash
)(.
))
Itchy skin
)(.
))
and diarrhea
)(.
))
. The severity and frequency of adverse events observed were consistent with those observed in other clinical studies.
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dd ,) dd dh , dd )
dd ,) dd dh , dd [Indications]
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dd ,) dd dh , dd )
dd ,) dd dh , dd This product is suitable for the treatment of locally advanced or metastatic non-small cell lung cancer that has previously received chemotherapy (
)
). Previous chemotherapy treatments mainly referred to platinum and docetaxel treatments.
dd ,) dd dh , dd )
dd ,) dd dh , dd The efficacy of dd in patients with locally advanced or metastatic non-small cell lung cancer who have failed chemotherapy is established based on objective response rate indicators , there are no controlled studies showing clinical benefit in improving disease-related symptoms and prolonging survival. The existing data on the use of this product in the second-line treatment of non-small cell lung cancer are only based on uncontrolled clinical studies and need to be further confirmed by well-designed controlled clinical trials.
dd ,) dd dh , dd )
dd ,) dd dh , dd For the first-line treatment of non-small cell lung cancer, the results of two large randomized controlled clinical trials showed that
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: Platinum-based doublet chemotherapy did not show any benefit when combined with this product. Therefore, gefitinib is not suitable for this treatment.
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dd ,) dd dh , dd )
dd ,) dd dh , dd [Usage and dosage]
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dd ,) dd dh , dd )
dd ,) dd dh , dd The recommended adult dose of this product is
)(
tablet
))
)
day
)
times, take orally on an empty stomach or with food.
dd ,) dd dh , dd )
dd ,) dd dh , dd If you have difficulty swallowing, disperse the tablet in half a glass of drinking water
)(
Non- Carbonated drinks
))
, other liquids are not allowed. Throw the tablets into the water without crushing, stir until completely dispersed
)(
It will take about
)
minutes
))
Drink immediately Administer liquid medicine. Rinse the cup with half a cup of water and drink. The medicinal solution can also be administered through a nasogastric tube.
dd ,) dd dh , dd )
dd ,) dd dh , dd There is no need to adjust the dosage due to the following conditions
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: age, weight, gender, Race, renal function, moderate to severe liver impairment due to liver metastases.