Which is the most effective treatment for ovarian cancer?

Ovarian cancer is one of the diseases with high mortality in women. Due to the lack of effective methods for early diagnosis of this disease, most patients are already in the advanced stage when they seek treatment. The treatment effect is poor
The annual survival rate is generally low
%~%
How should the surgical treatment of ovarian cancer be carried out
?
.>
Principles of surgical treatment of ovarian cancer:
.> Due to the development of medicine and the accumulation of clinical experience That is, there are also new perspectives on the principles of surgery for malignant ovarian tumors. In the past, it was advocated to remove the entire uterus, omentum and appendix in two pieces, but such surgery cannot reduce the recurrence of tumors. The principle of surgery in recent years is to remove the tumor completely or basically completely, including the primary spread and metastasis, and the diameter of the cancer should not exceed
. Its clinical significance is to reduce the tumor volume to the maximum extent and reduce the tumor cells to the minimum, so it is collectively referred to as tumor. Cytoreduction or tumor cell reduction. Tumor reduction surgery can be divided into three types according to the scope and complexity of the operation ①
Simple tumor resection (
including uterine appendages, etc.) ②
Maximum tumor surgery ③
Pelvic cavity Organ removal surgery
. In conjunction with other adjuvant treatments, survival rates can be improved and prognosis improved.
.> Surgical treatment of ovarian cancer
, on uterus and adnexectomy, some authors reported
unilateral adnexectomy and
routine bilateral adnexectomy for stage I ovarian cancer. The annual survival rates of lateral adnexa+
hysterectomy (
radical surgery)
are %
and % respectively
There is no significant difference between the two, so it is suggested that It is feasible for stage I patients to undergo only unilateral adnexectomy. This method not only solves a fertility problem, but the ultimate goal is to maintain the balance of the female's internal environment. However, the risk of delaying radical surgery should not be ignored because of overemphasis on preserving fertility.
.> However, many authors have proposed that bilateral adnexectomy should be performed whenever ovarian malignant tumors are diagnosed. Mainly considering that patients with ovarian cancer have a higher chance of having bilateral disease, retaining the unaffected ovary means remaining latent cancer foci. Some authors have suggested that the uterus is also a site where tumors can easily spread. According to statistics, about %~%
of ovarian cancer metastasizes to the uterus and %
is accompanied by endometrial cancer and precancerous lesions. Therefore, it is proposed that hysterectomy should be performed at the same time. .
.> At present, most experts believe that comprehensive consideration should be based on age, marital status, clinical staging, tissue type, cell differentiation, tumor size, fertility requirements, etc., and must not be blindly engaged in reserving period patient requirements
The contralateral ovary can be preserved when contralateral ovarian wedge biopsy is confirmed to be negative for fertility. Taking into account the residual ovarian function, the substantial part of the resection is generally not more than/
. Lang Jinghe
believes that function-preserving surgery is feasible only in high-selective situations, that is, preserving the contralateral appendage and uterus, but it must meet all the following conditions:
.> ①
The patient is young and desires to have children
. > ②
Stage
.> ③
The cells are well differentiated
or borderline
.> ④
The tumor is smooth and active
.> ⑤< br/>Contralateral ovarian appearance was normal and biopsy was negative
.> ⑥
Peritoneal cytology was negative
.> ⑦
Peritoneal multi-point biopsy was negative
.> ⑧< br/>If there are follow-up conditions or it is recommended that the uterus and contralateral appendage should be removed after completion of childbirth.
.>
About omentectomy: The omentum is one of the earliest metastasis sites of ovarian cancer, with a metastasis rate of %~%
.
and r
Reports
Omentectomy for stage ovarian cancer
Annual survival rate %
Unresected
Annual survival rate %
. In recent years, many materials have proven that the omentum is an important site for subclinical metastasis. Most scholars have included omentectomy as part of ovarian cancer surgery. Its advantages
:
.> ①
Reducing the tumor volume is beneficial to other postoperative treatments
.> ②
Reduce the production of ascites
.> ③< br/>Promote the uniform spread of isotopes in the abdominal cavity
.> ④
Relieve the patient's abdominal pain symptoms. Chen Huijian
believes that if patients need to retain the large membrane network, they must have enough biopsy tissue to confirm that there is no metastasis before the large membrane network can be retained
and
The above patients routinely undergo omentectomy.
.>
, Regarding appendectomy: Some scholars have used ovarian cancer surgery to understand the incidence of appendiceal metastasis. Intraoperative appendectomy
early cases (ⅰ
, ⅱ
Stage)
No appendiceal metastasis was found. The incidence rates of appendiceal metastasis in stage III
and IV
cases were %
and %
in right primary tumors< br/>One case involved the appendix (.%)
One case of left primary tumor
One case involved the appendix (.%)
.
.> It is speculated from the data that the appendix is not the first site of ovarian cancer metastasis but is caused by direct tumor infiltration adjacent to the anatomical site of the ovarian tumor. Domestic scholars believe that appendiceal metastasis of ovarian cancer is closely related to the stage and has nothing to do with the histological type of the tumor. However, most scholars believe that mucinous cystadenocarcinoma cases are prone to appendiceal myxoma and mucinous tumor rupture to produce diffuse peritonitis, so they are removed during surgery. The appendix is appropriate. It is currently advocated that appendectomy is not necessary for patients with stage I~II
can help reduce postoperative residual disease.
.>
, Removal of retroperitoneal lymph nodes: The document states that the metastasis of retroperitoneal lymph nodes in each stage is about %
ⅱ
It is about % in each stage
ⅲ
The period is about %
. Johnson (
Compilation of papers at the First National Gynecological Cancer Surgery Conference)
pointed out that if the patient's condition and technical conditions permit, all patients with ovarian malignant tumors should strive to undergo retroperitoneal lymph node dissection during surgery. This can Achieve both diagnosis and treatment purposes.
.> For advanced epithelial ovarian cancer, retroperitoneal lymph node dissection can improve the survival rate under the premise of ideal residual tumor diameter
during debulking surgery. On the contrary, if debulking surgery is not ideal, retroperitoneal lymph node dissection cannot improve the survival rate. The current popular view is that lymph node dissection is required for ovarian cancer surgery. The method can remove all or part of the main tumor (
Maximum residual tumor diameter)
In cases of initial surgery combined with dissection, laparotomy is required or there is unavoidable large residual size. Dissection is not performed when the lesion is localized.
.>
, Success rate of ovarian cancer surgery Secondary exploration: Secondary exploration Purpose: It is performed to understand the treatment response of ovarian cancer patients when they have fully recovered clinically after surgery and sufficient chemotherapy. re-exploration surgery. There are many ways to monitor ovarian treatment due to the development of imaging technology (such as

,
super or
line, etc.)
but there is no single imaging technology Can accurately replace secondary exploration. Secondary exploration is currently a relatively reliable and safe method to understand the treatment response of ovarian cancer after chemotherapy. Most scholars agree that the time between surgery and the last chemotherapy should be ~
weeks. If there are no visible lesions after careful exploration, routine multi-point biopsy should be performed at the suspicious site or the above-mentioned exploration site. Generally, a piece of left and right tissue is taken for pathological examination. Secondary exploration can understand the effect of chemotherapy and make appropriate decisions to stop or continue chemotherapy and change chemotherapy drugs for re-excision of early recurrent lesions or original residual tumors as appropriate.
.>
Second cytoreduction surgery. Some authors have reported that using
a course of enhanced intravenous chemotherapy followed by secondary cytoreduction surgery can save most patients with massive tumors. Achieve appropriate levels of cytoreduction. r (
Year)
Considered that repeat cytoreduction may not be of much benefit to patients with recurrence. Surgery should be performed very carefully on an individual basis, otherwise it will affect the success rate of ovarian cancer surgery.
.>
Preventive oophorectomy: Women with ovarian cancer syndrome often have chromosomal dominant inheritance tendencies in their family pedigrees. The risk of ovarian cancer in their lifetime is very high, so it should be performed after completing the family planning. Ovarian removal surgery may prevent the onset of ovarian cancer Preventive oophorectomy may delay the onset of ovarian cancer in your forties. In short, with the continuous accumulation of clinical experience, many innovations have been made in the surgical management of ovarian cancer, which has expanded the necessary scope of surgery and improved the success rate of ovarian cancer surgery.
.>
Palliative surgery: Palliative surgery for advanced ovarian cancer is usually a surgery to relieve intestinal obstruction and is treated in the same way as intestinal obstruction caused by other causes. About %
of patients with intestinal obstruction can relieve the obstruction through surgery. However, the complications and mortality rate of surgical treatment for patients with ovarian cancer intestinal obstruction are quite high. Therefore, some people suggest that treatment should be based on the judgment and experience of the gynecologist and whether the patient has palliative effect and chance of recovery, and adopt an individualized principle for treatment.
.> Ovarian cancer is one of the most common tumors in women. Ovarian cancer ranks first among all types of gynecological tumors and poses a serious threat to women's lives. Its five-year survival rate is only %
~%
. According to epidemiological statistics, ovarian cancer is more likely to occur in women with ovarian insufficiency, such as those with delayed menarche, early menopause, dysmenorrhea, singleness, infertility, frequent induced abortions, and those with a family history. Because the ovaries are located deep in the pelvic cavity, there may be no or mild symptoms in the early stages of the disease, such as a mass in the uterine appendage, accompanied by unexplained gastrointestinal symptoms such as loss of appetite, abdominal distension, and weight loss
.> Because ovarian cancer is asymptomatic in the early clinical stage, it is difficult to identify its tissue type and benign and malignant. During laparotomy, only % of ovarian cancer tumors are found to be limited to the ovary
Most of them have spread to both sides of the uterus. Attachment to the omentum and various pelvic organs, so ovarian cancer is indeed a big problem in diagnosis and treatment.
.> Over the years, experts have invested a lot of energy in clinical research on ovarian cancer, trying to find high-efficiency and low-toxic anti-ovarian cancer drugs. Ginseng is a precious traditional Chinese medicinal material that has been studied much since ancient times. Modern medical research shows that ginseng has various biological activities such as anti-tumor and anti-radiation. Its main active ingredient is ginsenosides. So far, more than a dozen saponins have been isolated from ginseng and their structures have been determined. Through comparison of the anti-tumor effects of various ginsenosides, it was found that ginsenosides have the strongest ability to inhibit cancer cell proliferation among ginsenosides. The main anti-cancer active ingredient. Ginsenosides are effective against a variety of tumors by inhibiting cancer cell proliferation and inducing cancer cell differentiation and apoptosis, and also provide a new weapon for the treatment of ovarian cancer.
.> Zhu Junrong, Sun Jianguo and others studied the effect of ginsenoside
on the proliferation and apoptosis of estrogen-dependent human ovarian cancer
cells. The results showed that the growth of D
cells
was inhibited in a dose-dependent and time-dependent manner. /
Light microscopy showed that the growth of D
cells was
After the action, there were obvious morphological changes of apoptosis
Flow cytometry test confirmed that
it can induce D
cell apoptosis within a certain concentration range and block the cell cycle in
period and increased expression. It shows that
it can inhibit the proliferation of D
cells and induce their apoptosis and is effective in ovarian cancer.
.> Ginsenosides
It also has good safety. Gao Feng and others from Jilin Ginseng Research Institute have experimentally confirmed that ginsenosides
have effects on the nervous system, respiratory system, and cardiovascular system of normal mice and dogs. There is no obvious effect on the system, which is significantly different from other anti-cancer chemotherapy drugs.
.> Because of the high efficiency and low toxicity of ginsenosides
it can kill tumor cells without damaging normal cells. It can also activate the function of immune cells to exert the body's own immune system to clear cancer cells, which is more beneficial to patients. Rehabilitation.
.> Ginsenosides
【Applicable】
.>
Patients who have just been diagnosed with cancer but are still difficult to determine a specific treatment plan can control the development of the disease and prevent tumor metastasis and spread after taking it.
.>
, Taking it by patients before surgery can shrink the tumor, reduce the scope of surgery and improve the success rate of surgery
.>
, Taking it by patients after surgery can eliminate the remaining cancer cells and prevent recurrence, At the same time, transfer can accelerate incision healing, anti-inflammatory and analgesic, prevent and treat infection, and prevent complications
.>
. Patients who are undergoing radiotherapy and chemotherapy can eliminate toxic side effects, enhance drug sensitivity and improve efficacy
/> .>
For patients with acute, severe and advanced cancer who are weak, taking ginsenoside
can quickly improve their immune function, enhance their anti-cancer ability, improve their quality of life and extend their life expectancy
.>
. Regular use by patients in the recovery phase of cancer can effectively eliminate residual tumor cells and microscopic lesions in the body, enhance physical fitness, consolidate curative effect, and prevent recurrence and metastasis.
.> Ginsenosides
Bringing you new hope Now the ginseng saponins
The one with the highest content is Jinxing Capsule produced by Zhejiang Yake Pharmaceutical, which contains up to .%
.> Today The main functional ingredient of Xing Capsule is ginsenoside
content
which is known as the killer of cancer.
Since it entered the market, it has been recognized by the majority of cancer patients and their families.
.> The production and sales of Jinxing Capsules (
Ginsenosides)
are undertaken by
Zhejiang Yake Pharmaceutical Co., Ltd., a member company of Hainan Asia Pharmaceutical Group. The company adheres to advanced and modern marketing concepts and has the courage to innovate. In the sales of
Jinxing
capsules, it adopts the
Internet direct sales model, eliminating agents, distributors and distribution in traditional marketing. Channels such as merchants and intermediate links such as pharmacies and stores greatly reduce marketing costs. The purpose is to benefit consumers so that consumers can truly enjoy cheap and high-quality products. At the same time, online direct sales do not have to worry about buying fake and shoddy products because they buy directly from manufacturers. . Therefore, it is currently not sold in pharmacies. Note: At present, Jinxing Capsules (
Ginsenoside r)
are only shipped directly from the manufacturer.
.> Ginsenosides
Manufacturer Consultant Hu
Hour consultation hotline: (
Consultant Hu)
.> For more cancer rehabilitation consultation contact
:
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