Sofosbuvir price 13621079267 Sofosbuvir purchasing price in India

Sofosbuvir, English name
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is a new drug developed by Gilead for the treatment of chronic hepatitis C. ,
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Japan has been approved for marketing in the United States by the U.S. Food and Drug Administration
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Nikkei European Medicines Agency
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Approved for marketing in EU countries . The drug is not yet available in China and can only be obtained from overseas hospitals.
< , Song Dynasty>The drug is the first drug that can safely and effectively treat certain types of hepatitis C without the need for interferon. Clinical trials confirmed the overall sustained virological response rate of the drug combined with pegylated interferon and ribavirin against
Song Dynasty> and
Song Dynasty> hepatitis C
(R) Song Dynasty> Up to
% Hepatitis C, the drug combined with ribavirin has a
%-% Hepatitis C effect against
Arial> For hepatitis C, the
R 宋体> of this drug combined with ribavirin is
%-% 宋体>. It is worth mentioning that the clinical trials of sofosbuvir also included some patients with hepatitis C and cirrhosis, and the efficacy was also significant.
< , Song Dynasty>The new drug Sofosbuvir for the treatment of hepatitis C has put the controversial US health care reform into another dilemma. Unable to solve the health insurance cost problem, some states, represented by Oregon, are seeking ways to limit the supply of the drug. As a result, the expanded Medicaid program proposed in President Obama's health care reform plan has been greatly reduced.
< , 宋体>Usage and dosage
< , 宋体>Each tablet
宋体>, one tablet a day, take on an empty stomach or with food
< , 宋体>Can be combined with ribavirin Or combined with ribavirin
+ peginterferon to treat chronic hepatitis C
() 宋体>.
< , Song Dynasty>The recommended combination treatment plan is as follows:
< , Song Dynasty>Single infection
< , Song Dynasty>or
/- Song Dynasty>Combined infection treatment plan Treatment duration< br/> < , 宋体>gene
宋体>or
宋体>Sofosbuvir
+ 宋体>pegylated interferon
宋体>&
+ Arial>Ribavirin
Arial>Zhou
< , Arial>Gene
Arial>Sofosbuvir
+ Arial>Ribavirin
Arial >zhou
< , 宋体>gene
宋体>Sofosbuvir
+ 宋体>ribavirin
宋体>zhou
< , 宋体>cannot be used Patients with chronic hepatitis C type of interferon may consider using sofosbuvir combined with ribavirin for treatment for
Song Dynasty> weeks.
< , Song Dynasty > Hepatocellular carcinoma patients awaiting liver transplantation should be treated with sofosbuvir combined with ribavirin for chronic hepatitis C for
Song Dynasty> weeks or until liver transplantation, whichever occurs first .
< , Song Dynasty>Dosing recommendations cannot be made for patients with severe renal impairment or end-stage renal disease.
< , 宋体>Dosage form
< , 宋体>Each tablet:
宋体>.
< , Song style>Contraindications
< , Song style>Sofosbuvir combined with pegylated interferon
Song style>&
+ Song style>Ribavirin, or alone When used in combination with ribavirin, all contraindications for peginterferon or ribavirin also apply to combination therapy with sofosbuvir.
< , ? 宋体> Since ribavirin may cause fetal congenital malformation or stillbirth,
宋体> Therefore, sofosbuvir combined with pegylated interferon&
+ 宋体> is beneficial Bavirin, or sofosbuvir alone in combination with ribavirin should be contraindicated in pregnant women and men whose partners are pregnant.
< , 宋体>Indications and uses
< , 宋体>Sofosbuvir is a type of hepatitis C virus
() 宋体>Nucleotide analogues
宋体> Polymerase inhibitor, suitable for use as a combination component in a combined antiviral treatment regimen for the treatment of chronic hepatitis C
() 宋体> infection.
< , Song Dynasty> Sofosbuvir has been tested to be effective in treating gene
Song Dynasty>,
Song Dynasty>,
Song Dynasty> or
Song Dynasty> type of hepatitis C. Patients, including hepatocellular carcinoma subjects who meet Milan criteria and are waiting for liver transplantation and co-infected subjects.
< , Song Dynasty>Warnings and Precautions
< , Song Dynasty>Pregnancy: Ribavirin may cause fetal congenital malformations or stillbirth, and animal experiments show that interferon can cause miscarriage. Therefore, female patients taking this drug and the spouses of male patients should avoid becoming pregnant. Before starting treatment, patients must have a negative pregnancy test, use at least two non-hormonal methods of contraception, and undergo monthly pregnancy tests.
< , Song Dynasty>Adverse Reactions
< , Song Dynasty>The most common known adverse reactions caused by sofosbuvir combined with ribavirin
( Song Dynasty>The incidence rate is equal to or greater than
% Song Dynasty>, all grades
) Song Dynasty> is caused by headache and fatigue
Song Dynasty> Sofosbuvir combined with pegylated interferon
Song Dynasty> & ribavirin has caused The most common adverse reactions include fatigue, headache, nausea, insomnia and anemia.
< , 宋体>Drug interactions
< , 宋体>Powerful intestinal glycoproteins
(-) 宋体>Inducers
( 宋体> Such as rifampicin
/>) Arial > May alter drug plasma concentrations of sofosbuvir. Before use, please read the complete package insert for drug-drug interactions.
< , Song Dynasty > Medication for special groups
< , /- Song Dynasty > Co-infected patients: The safety and effectiveness of this drug have been confirmed by research.