Is it effective to take ginsenoside RH2 for laryngeal cancer?

large amount of clinical practice has proven that high-dose radiotherapy and chemotherapy for patients with intermediate and advanced stages or repeated chemotherapy for patients who have developed resistance can only lead to a weakened life and accelerate the patient's death.
In clinical practice, it is often seen that the cause of death of patients is not caused by the cancer itself but due to unscientific and inappropriate lethal treatments. For example, after repeated intervention for liver cancer, ascites, jaundice, and other liver failure may lead to death. Pleural effusion in lung cancer may lead to respiratory failure and death after chemotherapy. Gastric cancer and intestinal cancer may suffer from nausea and vomiting after chemotherapy. Patients may become more exhausted and die due to decreased white blood cells. Patients may die due to infection.
The first choice for traditional Chinese medicine treatment is yew as the main component of Chinese herbal medicine, but yew cannot be taken alone. Scientific research shows that yew is very toxic. Normal people may suffer from severe toxic side effects such as suppression of bone marrow hematopoietic function and decrease in white blood cells. The main manifestations are dizziness, dilated pupils, nausea, vomiting, diffuse abdominal pain, muscle weakness, etc. In severe cases, bradycardia, cardiac arrest or Not to mention death, cancer patients have low resistance and weak body, which will be more dangerous if taken alone
This type of traditional Chinese medicine can make up for the shortcomings of surgical treatment, radiotherapy and chemotherapy, not only consolidate the effect of radiotherapy and chemotherapy, but also eliminate the toxic and side effects of radiotherapy and chemotherapy. The important thing is that it can cut off the replication function of cancer cells, that is, cut off the important division method of cancer cells, tubulin synthesis, so that the cell volume gradually shrinks, forming a stable anti-cancer cell in blood vessels, thereby improving the metabolic function of the human body, that is, by inhibiting the respiration of cancer cells. The cancer cells are deprived of oxygen and ischemia and no longer fission to achieve the purpose of curing cancer.
Ginsenosides and health
King of immunity, hope for cancer patients, good news for the frail and sick
Ginseng is a traditional precious medicinal material in my country with a history of medicinal use in recent years. As early as the Warring States Period, the good doctor Bian Que recorded the medicinal properties and curative effects of ginseng. In the "Shen Nong's Materia Medica" of the Qin and Han Dynasties, it was recorded that it can tonify the five internal organs, calm the spirit, soothe the soul, stop panic, remove evil spirits, improve eyesight, improve intelligence, and prolong life after long-term use. Since ancient times, ginseng has been regarded as a treasure for curing diseases and maintaining health, and is known as the king of herbs.
With the advancement of modern medical technology, ginseng research has also made major breakthroughs. Medical scientists have gradually unveiled the mystery of ginseng. The chemical composition of ginseng is relatively complex, including ginsenosides, amino acids, peptides, polysaccharides, vitamins, fatty acids, and sterols, but the main active ingredient is ginsenosides. At present, nearly ginseng saponin monomers have been isolated, including R and R with very low content.
Different types of ginsenosides have different effects. For example, RR has the effect of lowering blood lipids and R has the function of promoting and enhancing memory and enhancing the heart. RR has anti-aging and antioxidant effects, which can effectively improve immune function. In addition, some ginsenosides also have anti-fatigue, anti-hypoxia, anti-radiation and other effects.
In addition, scientists have found that some ginsenosides have anti-cancer activity, such as RRd, RR and R, which have certain inhibitory effects on tumors, among which the one with the strongest anti-tumor activity.
Although the content of ginsenosides is very low, its medicinal value is very high. Ginsenosides can not only be used to improve immune function and prevent various diseases including cancer, but can also be used to relieve fatigue and improve sub-health, and can also be used as an auxiliary treatment for cancer.
Ginseng saponins improve immune function and maintain health and stay away from disease
Immune function is the body's own defense mechanism. It is the body's recognition and elimination of any foreign matter (virus, bacteria, etc.) that invades from the outside, and deals with aging, damage, death and degeneration of itself. cells and their ability to recognize and deal with mutant and virus-infected cells in the body.
The stronger the immune function, the better the human body's ability to resist the invasion of foreign diseases, and the better the body's physical condition will be. On the contrary, if the immune function is low, the body's resistance to invading pathogens from the outside is weak, and the person is easily attacked by various diseases.
In fact, the occurrence of many malignant diseases is also closely related to low immune function, such as malignant tumors. When the immune system is destroyed, the immune system loses its surveillance function. Cells with genetic mutations cannot be detected and repaired in time. The cells proliferate indefinitely and are prone to cancer. If the immune function is enhanced through means such as medicine and exercise, the chance of contracting tumors will be greatly reduced, thereby achieving the effect of preventing tumors.
Experiments have proven that ginsenosides have a strong effect in improving the body's immune function. The Dalian Institute of Traditional Chinese Medicine conducted a test on the impact of ginsenosides on immune function using the phagocytic cell activity and activity of macrophages as indicators. Test results show that ginsenosides significantly improve immune function
Two ginsenosides are effective in anti-fatigue and improving sub-health
Sub-health is a unique health problem in modern society.
Sub-health is a state of low physiological function between disease and health or a precursor to disease. Typical symptoms of sub-health include poor sleep quality, forgetfulness, soreness in the neck, shoulders, back and back, difficulty concentrating, loss of appetite, anxiety, depression, fatigue, weakness, dizziness, shortness of breath, etc.
Century society has entered an era of rapid economic development. The pace of work and life has accelerated, and people's physical and mental pressure has increased. Sub-health problems have become more and more serious. Surveys show that the incidence rate of sub-healthy people in our country is between % and %, and they are mainly high-end people who are engaged in mental work and suffer from excessive mental stress. Sub-health has become an invisible killer that seriously endangers people's physical and mental health.
How many white-collar social elites are prospering in their careers, and their bodies are deteriorating, and they are suffering from sub-health. Not only is their quality of life seriously reduced, some people even cannot resist the strong pressure of work and family, and have a mental breakdown. They engage in excessive behavior and bring consequences to their family and society. serious instability.
Because although sub-health has functional changes, there are no obvious organic lesions, it is highly concealed and most easily ignored. At the same time, it is uncertain whether sub-health will develop into serious organic lesions, so it is necessary to attract attention. Moreover, in order to prevent problems before they occur, sub-health itself is a problem that needs to be solved.
"Huangdi Neijing" says, "The sage does not cure the disease, but the disease is not cured, the disease is not cured, the disease is not cured, the disorder is treated, and the disorder is not disordered." Isn't it too late for a husband's disease to become a problem and then treat it after it has become a disease? For example, if he is still thirsty, he goes to dig into the well and cast a cone? From this, we can clearly see that our ancestors have realized the importance of taking precautions against diseases before they occur. . If sub-health problems are not solved in time, it will be too late by the time sub-health evolves into serious diseases.
There are many causes of sub-health. Domestic and foreign studies have found that the main causes of sub-health are physical and mental fatigue, decreased immune system function caused by early stages of aging diseases, and imbalances among various body systems.
Therefore, improving social adaptability, enhancing self-psychological adjustment, reducing stress, relieving fatigue, and improving immune function are important means to improve sub-health.
In addition, scientists have also proved through various experiments that ginsenosides also have obvious effects in resisting fatigue, accelerating physical recovery and improving labor efficiency. Therefore, ginsenosides can play an important role in improving sub-health.
Harbin Medical University conducted scientific experiments on the anti-fatigue effects of ginsenosides. Test results: Oral administration of different doses of ginsenosides to test subjects can significantly extend their weight-bearing swimming time, reduce liver glycogen consumption, reduce serum urea levels during exercise, and significantly inhibit the increase in blood lactate in test subjects after exercise. Therefore, it is believed that ginsenosides can relieve physical fatigue in a dose-dependent manner. That is, the higher the dose of ginsenosides, the more significant the anti-fatigue effect will be (that is to say, obtaining a certain therapeutic effect is the key).
Panax ginseng saponins have significant auxiliary effects and are good news for cancer patients
According to statistics, there are about 10,000 malignant tumor patients in the world and about 10,000 cancer deaths occur in my country every year. Malignant tumors have surpassed cardiovascular and cerebrovascular diseases to become the number one killer of human health. Human beings are tortured by the devil of cancer.
Many outstanding elites, celebrities and dignitaries who were in their prime died of cancer at a young age, leaving behind their money, honor and status and leaving their families with pain before they could enjoy the success they had worked hard for. I leave endless regrets to myself and my family, and endless grief and longing to the society.
It is regrettable that the rapid development of modern medicine has not only failed to develop effective methods and drugs to cure cancer, but it has also been unable to prevent the development and upward trend of cancer. Although surgery, radiotherapy, and chemotherapy have a positive therapeutic effect, at the same time, radiotherapy and chemotherapy have no selective killing of normal tissue cells and can cause toxic reactions in important organs of the body. This has brought great tissue damage and toxic side effects to patients, causing some patients to die not from cancer but from over-treatment of cancer.
Therefore, how to effectively curb cancer? How to improve the efficacy of chemotherapy drugs and reduce the toxic and side effects of radiotherapy and chemotherapy? How to reduce the pain of cancer patients during cancer treatment and survival with tumors has become a focus issue that has attracted more and more attention.
Research has found that ginsenosides are very effective in auxiliary treatment of enhancing efficacy and reducing toxicity. The specific performance is in the following aspects
When used in combination with chemotherapy drugs, it will show a synergistic effect to enhance the body's sensitivity to chemotherapy drugs and increase the effect of chemotherapy drugs
Ginsenosides can reduce the damage caused by antiradiotherapy and chemotherapy to peripheral blood cells The toxic side effects of radiotherapy and chemotherapy. Ginsenosides can overcome side effects such as bone marrow suppression, allergies, and organ toxicity caused by chemotherapy drugs. It can effectively protect the gastric mucosa, improve gastrointestinal function, significantly reduce nausea, vomiting, loss of appetite and other adverse reactions caused by radiotherapy and chemotherapy, and has obvious effects on preventing hair loss and the decrease of white blood cells. This helps to enhance the patient's tolerance to cancer pain and various treatments so that the treatment can be successfully completed
Ginsenosides can increase the specific and non-specific immune functions of cancer patients, improve the phagocytic ability of macrophages and the killing activity of cells Strengthen the patient's constitution, improve disease resistance, reduce the chance of infection, and reduce the chance of tumor recurrence
Ginsenosides are not toxic to normal cells and will not cure or damage the body. This has positive significance in enhancing patients' disease resistance, prolonging their survival time and improving their quality of life.
Reversal of tumor drug resistance The failure of clinical chemotherapy is often related to the resistance of tumor cells to chemotherapy drugs.
The anti-tumor mechanism of ginsenosides is as follows
Inhibit cancer cell proliferation
⑴ Mediate the synthesis of D
Because ginsenosides can directly inhibit the D replication and transcription ability of cancer cells after acting on cells Block the protein synthesis of cancer cells, thereby slowing down or stopping the proliferation of tumor cells.
⑵ Mediates and
Cyclins and cyclin-dependent protein kinase (D) form an important protein network that controls the cell cycle. Ginsenosides regulate the synthesis and metabolism of these important proteins in a timely manner and turn off the cycle switch of cancer cells to inhibit the proliferation of cancer cells.
Induces cancer cell apoptosis
⑴ Mediates cell phase
A variety of phase-related cell cycle regulatory proteins are regulated by ginsenosides, resulting in the arrest of phase cell growth induced by ginsenosides. Causes cell apoptosis to curb the crazy proliferation of tumors.
⑵ Inducing apoptosis of cancer cells by affecting genes
% of human tumors are related to gene mutations or deletions. Under the action of ginsenosides, the expression of mutant genes downregulates the amount of normal genes and rapidly accumulates, thereby promoting the apoptosis of tumor cells.
Induces differentiation of cancer cells
Ginsenosides can inhibit a variety of tumors by inducing differentiation, causing cancer cells to undergo differentiation changes not only in morphology but also in function, ultimately causing cancer cells to revert to normal cells. The directional evolution includes many signs of gene expression that are close to normal cells or even completely transformed into normal cells.
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