sofosbuvir buy india sofosbuvir price daclatasvir 13621079267

br , / ,, br b New drug Tarceva for the treatment of non-small cell lung cancer
br , / ,, br b [1] Mechanism of action
br , / ,, br b
b />
br , / ,, br b
br , / ,, br b small molecule compound, quinazoline analogue, molecular weight is , and is also an epidermal growth factor receptor ~ tyrosine Kinase R~ antagonist. It competes with adenosine triphosphate to bind to the catalytic site of the intracellular domain of receptor tyrosine kinase in cells, inhibiting the phosphorylation reaction, thus blocking downstream proliferation signaling and inhibiting ligand-dependent or extraligand-dependent /R in tumor cells. activity to inhibit cancer cell proliferation.
br , / ,, br b
br , / ,, br b [2] Indications
br , / ,, br b
br , / ,, br b United States Tarceva is approved as a second- or third-line treatment for advanced non-small cell lung cancer that has failed to respond to standard regimens. Some trial results show that its combination with chemotherapy does not increase the response rate or patient survival. For head and neck tumors, metastatic kidney cancer, pancreatic cancer, and breast cancer, Tarceva has shown promising effects when used in combination with chemotherapy or other targeted therapy drugs. .
br , / ,, br b
br , / ,, br b