Product Details
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[Drug name]: Iressa
Generic name: Gefiti Ni tablets
English name,,
Character: brown, round, biconvex, film-coated tablets with && printed on one side and && on the other side. Each tablet contains gefitinib. The total plasma clearance of gefitinib is approximately /. It is mainly excreted through feces, and about % is cleared through the kidneys in the form of prototypes and metabolites.
Functions and Indications
This product is suitable for the treatment of locally advanced or metastatic non-small cell lung cancer () that has previously received chemotherapy. Previous chemotherapy treatments mainly referred to platinum and docetaxel treatments. The efficacy for patients with locally advanced metastatic non-small cell lung cancer who have failed chemotherapy is established based on objective response rate indicators. There are no controlled studies showing clinical benefit in improving disease-related symptoms and prolonging survival. The existing data on the use of this product in the second-line treatment of non-small cell lung cancer are only based on uncontrolled clinical studies and need to be further confirmed by well-designed controlled clinical trials. For the first-line treatment of non-small cell lung cancer, the results of two large randomized controlled clinical trials showed that platinum-based dual chemotherapy regimens did not show any benefit after combined treatment with this product. Therefore, gefitinib is not suitable for this treatment. .
Indications
Gefitinib is suitable for the treatment of locally advanced or metastatic non-small cell lung cancer () that has previously received chemotherapy or is not suitable for chemotherapy.
Usage and Dosage
The recommended dosage is (tablets) once daily, taken on an empty stomach or with food. It is not recommended for children or adolescents. The safety and efficacy of this patient group have not been studied. No dose adjustment is required based on the patient's age, weight, sex, or renal function status and in patients with moderate or severe hepatic impairment due to liver metastasis from tumors.
Overdose
For overdose of Gemfil There is no specific treatment for TINI, and the specific signs of overdose are not yet known. In phase 1 clinical trials, a small number of patients received daily doses. An increase in the frequency and severity of some adverse reactions was observed, mainly rash and diarrhea. Adverse reactions caused by overdose should be treated symptomatically, especially severe diarrhea should be given appropriate treatment.
Specifications:/piece. Tablets
Storage: below ℃, stored in the original packaging (just keep it in a cool place indoors)
Validity period: years
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