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Is it okay to take ginsenoside RH2 during radiotherapy for nasopharyngeal cancer?

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  目前,由于环境与生活方式多方面因素,癌症发病率迅速攀升。癌症已成为疾病死因的第二位。这其中鼻咽癌已跃居头颈部恶性肿瘤发病率的第一位,其发病还具有地区聚集性和家族高发倾向性的特点。

  鼻咽癌一般都是放疗配合化疗进行的,在鼻咽癌放射治疗中,会出现放射反应,主要表现为头晕、头痛、失眠、容易发脾气、食欲下降、恶心呕吐等,并发症主要有口干、软组织纤维化、颞颌关节功能紊乱等。化疗可以导致白细胞下降、血小板减少和贫血,肝肾功能损害和严重的恶心呕吐等。对于这类情况,可以用中药调理,如服用人参皂苷RH2对于放化疗期间有消除毒副作用,增强药物的敏感性,提高疗效。

  1. 放疗期间鼻咽癌患者应多饮水,喝淡饮料、果汁、牛奶等。主食应以半流食或软烂食物为好,副食方面要多吃新鲜蔬菜、水果,尤其要多吃胡萝卜、荸荠、白萝卜、蕃茄、莲藕和白梨、柑桔、柠檬、山楂等果品。饮食口味要清淡甘润,又不宜过饮生冷,以免生寒伤胃,口含话梅、罗汉果、橄榄、青果等,可刺激唾液分泌,减轻干燥症状。

  2. 鼻咽癌放疗期间饮食应配餐辅食应少用生湿化痰、粘腻重浊、肥甘醇酿,可选用有化痰散结功效的食品,如海带、紫菜、龙须菜、海蛰等。出现头晕目眩,耳聋口苦、急躁易怒等肝火上炎症状时,宜选清肝泻热、滋阴潜阳之品以减轻症状,如菊花代茶,炒决明子代咖啡,食用苦丁茶、黄花菜、苦瓜、枸杞苗、李子、鲍鱼、芥菜等。

  3.放疗期间鼻咽癌患者多属气血不足,毒火上炎,食欲极差,所以鼻咽癌放疗期间饮食应刺激食欲,增加摄入是保证治疗的根本措施。故宜选易消化、营养充足,色香味俱佳的食品,如粥、羹、汤、汁等。调配饮食又应以滋润适口、芳香化浊为好,如冰糖苡米粥、香菜清炖大鲤鱼、鲜石榴、鲜乌梅、广柑、香橼、菠萝、青梅、菱角、荸荠、白梨等。平时口含藏青果和鲜山植,有消炎杀菌、清咽生津的作用。

  人参皂苷Rh2可预防和减少放、化疗毒副反应

  放、化疗是利用抗癌药物或放射线为治疗手段,对多种癌症具有较好的近期疗效。但放、化疗在杀伤癌细胞的同时, 也对正常组织细胞无选择性杀伤,通常称为放、化疗毒副作用或不良反应。临床上最常见的放、化疗不良反应有:

  1. 骨髓抑制:放、化疗引起的不良反应最显著的特点是常攻击那些增殖旺盛的组织、器官,尤其是对血液系统损伤是临床最常见的。轻度不良反应可引起外周血细胞呈不同程度减少,但停止治疗后可自行恢复;严重的不良反应可导致骨髓抑制,致使病人外周血细胞显著降低,并因白细胞显著减少而继发严重的感染,血小板显著降低而招致致命的出血。因此,骨髓抑制是影响抗癌治疗顺利进行以及影响临床疗效的关键。

  2. 胃肠道不良反应:放、化疗可引起胃肠道黏膜损害,出现程度不同的胃肠道不良反应。轻者胃部不适,恶心欲吐,不思饮食等;重者胃痛、腹痛、呕吐不止、严重影响进食,甚至可导致水、电解质与酸碱平衡紊乱,严重营养不良等,从而降低病人生活质量。

  3. 脏器功能损害:几乎所有的化疗药物都可引起脏器损害:

  1) 肝脏损害:轻者出现腹胀、恶心、食欲不振、甚至黄疸等,严重者可出现肝脏功能衰竭;

  2) 肾脏损害:早期无明显症状,时常见有尿少等临床表现。尿素氮异常,血肌酐升高往往是慢性或急性肾脏功能不全的征兆;

  3) 心脏损害:可导致原有心脏病的加剧,并可诱发严重的心律失常,其表现就是心动过速、早搏、心动过缓等,严重的可导致心力衰竭。

  4. 免疫功能降低:癌症病人机体免疫功能处于明显紊乱状态,失去了对癌细胞的监控能力,并错误的将癌细胞看成是自身的一部分,并允许癌细胞在体内持续生长与高速增殖。同时,放、化疗又进一步摧毁病人的免疫功能,导致免疫功能进一步下降。并由此招致严重的感染,促使病情进行性加重或恶化。

  5. 另外,放、化疗也可引起脱发、皮肤损害等。

  综上所述,放、化疗引起的不良反应不仅影响了病人的生活质量,而且可导致癌症治疗失败,最终使病人生存期缩短。因此,克服放、化疗导致的不良反应一直是临床研究的重点。

  根据现有实验研究文献,Rh2能在以下几方面对抗放、化疗不良反应。

  1. 能够对抗放、化疗对外周血细胞造成的伤害,对骨髓造血功能也具有明显的保护和促进作用。有效预防放、化疗骨髓损伤,有利于放、化疗周期的完成与提高临床疗效。

  2. Rh2不但是补益治疗的强壮剂,也是包括胃肠在内的多种脏器组织功能的保护剂,能够有效的保护胃黏膜,改善胃肠功能,增加食欲与饮食量,明显减轻放、化疗导致的胃肠道不良反应。

  3. Rh2能够增加癌症病人特异性与非特异性免疫功能。增强病人体质,提高抗病能力,减少感染机会,增加病人组织器官对放、化疗的耐受性。

  4. 通过保护脏器功能而对抗放、化疗导致的脏器功能损害。

  人参皂苷rh2厂家胡顾问24小时咨询热线:18969068960(胡顾问)

  更多肿瘤康复咨询联系QQ1906227307,也可通过手机号QQ直接添加微信咨询

 

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