Product Details
[Ingredients] _b> #>, each tablet contains erlotinib (in the form of erlotinib hydrochloride)
[Characteristics]<
#, #Round, biconvex, white coating piece.
[Mechanism of Action]
The anti-tumor mechanism of #, #r is mainly to inhibit the intracellular phosphorylation of epidermal growth factor (R) tyrosine kinase.
【Pharmacokinetics】
#, #r% absorbed after oral administration, half-life is about hours, and is mainly eliminated by metabolism. The bioavailability of r after oral administration is approximately %, and peak plasma concentration is reached after several hours. Pharmacokinetic analysis of the patient treated with a single drug r showed that it takes - days to reach stable blood concentration. The patient's age, weight, and gender have no significant relationship with the drug clearance rate. Smoking can increase the drug clearance rate by %.
[Indications]
#, #r is used for the third-line treatment of locally advanced or metastatic non-small cell lung cancer that has failed two or more chemotherapy regimens.
【Contraindications】
# , #Contraindicated for those who are allergic to this product and its ingredients.
[Adverse Reactions]
#, #The most common adverse reactions are rash and diarrhea, the incidence rates of rash and diarrhea are % and % respectively, the median appearance time of rash is days, and diarrhea is The bit appearance time is days. Adverse reactions with an incidence rate greater than % include: rash, diarrhea, decreased appetite, fatigue, dyspnea, cough, nausea, infection, vomiting, stomatitis, itching, dry skin, conjunctivitis, keratoconjunctivitis, and abdominal pain.
[Precautions]
#, #This product must be used under the guidance of doctors with experience in the use of such drugs, and can only be used in the national tumor drug clinical trial base or tertiary A hospitals.
[Usage and Dosage]
#, #The recommended dose of erlotinib alone for non-small cell lung cancer is /day, taken at least one hour before or one hour after eating. Continue treatment until disease progression or intolerable toxicity occurs. There is no evidence that patients benefit from continuing treatment after progression.
[Specifications]
#, #/piece
[Storage]
#, #℃ stored, ℃ ~ ℃ is also acceptable.
【Packaging】
#, #blister pack/box.
【Validity Period】
# , # months
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