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Ursodeoxycholic acid
Chinese name ursodeoxycholic acid
English name
Chinese alias, dihydroxycholestanoic acid, dihydroxycholestanoic acid ursodeoxycholic acid iso- Oxycholic acid, dihydroxycholic acid, dihydroxycholanic acid, dihydroxycholanic acid
English alias
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Bear Deoxycholic acid is a white powder, odorless and bitter in taste. This product is soluble in ethanol, insoluble in chloroform, soluble in glacial acetic acid, and soluble in sodium hydroxide test solution.
Melting point ~℃.
Physical and chemical properties Ursodeoxycholic acid, the main component is dihydroxycholestanoic acid, which is an organic compound, odorless and bitter. This product is soluble in ethanol, insoluble in chloroform, soluble in glacial acetic acid, and soluble in sodium hydroxide test solution. It is used medically to increase bile acid secretion, change bile composition, reduce cholesterol and cholesterol lipids in bile, and help the cholesterol in gallstones gradually dissolve.
Purpose Ursodeoxycholic acid can increase the secretion of bile acids, change the composition of bile, reduce cholesterol and cholesterol lipids in bile, and facilitate the gradual dissolution of cholesterol in gallstones. It is used for cholesterol stones that are not suitable for surgical treatment, but It cannot dissolve bile pigment stones, mixed stones and opaque stones. For cholecystitis. Cholangitis and indigestion also have certain effects.
Ursodeoxycholic acid can promote the secretion of endogenous bile acids, reduce reabsorption, antagonize the cytotoxic effect of hydrophobic bile acids, protect liver cell membranes, dissolve cholesterol stones, and have immunomodulatory effects. Ursodeoxycholic acid can also Increase the absorption of cyclosporine in the intestine
In 2018, the Ministry of Health promulgated the "Notice on the Interim Management Measures for the Drainage of Bear Bile", and the source of ursodeoxycholic acid has been changed to poultry bile. Our company has It is mainly extracted from goose gall.