Year1
- CAS号：
- 64-75-5
- 分子式：
- C22H24N2O8.HCL
- 分子量：
- 480.9
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Precautions Protect against moisture, store in a dark and ventilated place, and agglomeration will not affect Avoid mixing the drug with alkaline pesticide sewage, otherwise it will be easily ineffective. This drug is ready for use and the liquid cannot be stored for a long time.
Tetracycline hydrochloride is preferred for the treatment of non-bacterial infections such as chlamydial infection, rickettsial disease, mycoplasma pneumonia, relapsing fever, and is also used for brucellosis, cholera, tularemia, rat-bite fever, anthrax, tetanus, plague, actinomycetes Treatment of respiratory system, bile duct, urinary tract infections and skin and soft tissue infections caused by gangrene and sensitive bacteria.
Properties, uses and production processes Tetracycline hydrochloride is a broad-spectrum antibiotic that has a bactericidal effect at high concentrations. In addition to common gram-positive bacteria, gram-negative bacteria and anaerobic bacteria, most rickettsiae belong to the genus Mycoplasma. Chlamydia, Atypical Mycobacterium, Treponema, Actinobacteria, Bacillus anthracis, Listeria monocytogenes, Clostridium, Nocardia are sensitive to this product. This product is more effective against gram-positive bacteria than gram-negative bacteria, but enterococci and penicillin-resistant gonococci are resistant to it. This product has good antibacterial activity against Gram-negative bacteria such as Vibrio, Brucella, Campylobacter, and Yersinia, but has no antibacterial activity against Pseudomonas aeruginosa. The antibacterial mechanism is that the drug can specifically bind to the position of the bacterial ribosome subunit, preventing the connection of aminoacyl at this position, thereby inhibiting the growth of peptide links and affecting the synthesis of bacterial proteins to produce an antibacterial effect, and because it can Changes the permeability of the bacterial cytoplasmic membrane, making it easy to accumulate in the bacteria, achieving a rapid antibacterial effect. Tetracycline hydrochloride is the hydrochloride of tetracycline base. It is further synthesized and refined during the production process. It has high purity, low toxic and side effects, and long storage period. The oral absorption percentage is much higher than that of tetracycline base. After entering the human body, the blood concentration and urine concentration and bioavailability are higher than that of tetracycline base. It is safe, reliable and effective.
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