Ketoprofen: *CAS 22071-15-4 *Yuancheng

Ketoprofen* *Yuancheng
Chinese name Ketoprofen
Chinese synonym Ketoprofen Ketoprofen (benzoylphenyl) propionate methylbenzoylphenylacetate methyl Benzoylphenylacetic acid Methylbenzoylphenylacetic acid Euprofen (+) Benzoylphenylacetic acid
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Related Categories Carbonyl Compounds
Chemical Properties Appearance White or off-white crystalline powder, anti-inflammatory and analgesic.
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Packaging cardboard drum
Used for arylalkanoic acid compounds. It has analgesic, anti-inflammatory and antipyretic effects. The anti-inflammatory effect is stronger than that of ibuprofen, with fewer side effects and lower toxicity. It is easily absorbed from the gastrointestinal tract after oral administration. After the first dose, peak plasma concentration is reached in about an hour. / Last. It has strong binding force with plasma proteins in blood. Excretion rate in urine is one in hours. Mainly excreted in the form of glucuronic acid conjugates. Used for rheumatoid arthritis, rheumatoid arthritis, osteoarthritis, ankylosing spondylitis and gout, etc.
Drug Interactions Drinking alcohol and using it at the same time with other non-steroidal anti-inflammatory drugs will increase gastrointestinal tract inflammation. Side effects include the risk of ulcers.
When used together with aspirin or other salicylic acid drugs, the efficacy cannot be increased, but the incidence of gastrointestinal side effects and bleeding tendencies increases.
Used together with anticoagulants, it may increase the risk of bleeding.
This product can enhance the effect of anti-diabetic drugs and reduce the antihypertensive effect of anti-hypertensive drugs. When used together with corticosteroids, it can significantly slow down inflammatory symptoms.
It should not be used together with methotrexate to prevent poisoning.
When used together with probenecid, verapamil, and nifedipine, attention should be paid to lowering the dose. When used together with digoxin, attention should be paid to adjusting the dose of digoxin.