Why should radiotherapy be the first choice for nasopharyngeal cancer?

Nasopharyngeal cancer is one of the top ten malignant tumors with high incidence in my country. Generally speaking, the radical cure for malignant tumors is surgical resection, but nasopharyngeal carcinoma is an exception, and radiotherapy is the first choice. There are three reasons: Special anatomical location. Nasopharyngeal cancer occurs in a hidden, rectangular cavity with a vertical diameter of only .cm, shaped like a small matchbox. The posterior wall is the cervical vertebrae, and the top wall is the base of the skull. The rupture hole has the sublingual, glossopharyngeal, vagus, accessory nerves and important arteries and veins entering and exiting the cranial cavity. Nasopharyngeal cancer also invades the skull through this hole. There are large arteries, veins and Lymphoid tissue. It is difficult to perform radical tumor surgery in a small area surrounded by large blood vessels and cranial nerves, and it is even more difficult not to damage these important structures. Therefore, due to anatomical limitations, the conclusion that nasopharyngeal cancer surgery is not an ideal method is objective. According to.
The rapid development of lesions brings difficulties and limitations to surgery. The tumor expands upward into the middle cranial fossa, damages many cranial nerves, and metastasizes to the deep and upper cervical lymph nodes. The metastasis rate is as high as -1. It can also metastasize to the brain and neck at the same time, and can also metastasize to the distant liver. Nasopharyngeal cancer is mostly undifferentiated or poorly differentiated cancer with a high degree of malignancy. Only 10% of patients are diagnosed in the early stage, and most of the patients diagnosed are in the mid-to-late stage.
The effect of radiotherapy is good. Its annual survival rate can reach . , radiotherapy can restore the original structure, and the trauma is small, so depth lines, cobalt, and accelerators have become the main means of treatment.
Taking ginsenoside R during radiotherapy and chemotherapy can enhance the curative effect and help recovery
Generally speaking, doctors will check the liver function of the patient before and after chemotherapy. If the liver function is damaged, avoid it when choosing drugs, or choose drugs. Protect liver function. Some Chinese medicines can damage liver and kidney function, so many doctors may suggest that it is best to stop using Chinese medicines during chemotherapy.
However, preparations of natural anti-cancer active ingredients extracted from traditional Chinese medicine have an irreplaceable special role in cooperating with radiotherapy and chemotherapy. On the one hand, it makes up for the damage caused by radiotherapy and chemotherapy to all aspects of the body, improves the above-mentioned side effects, promotes the improvement of patients' self-repair ability, and on the other hand, it can reduce the emergence of chemotherapy resistance, thereby reducing the number of chemotherapy drugs.
Dr. Xu Jingda, director of the Chinese Pharmaceutical Association, honorary chairman of the National Ginseng Association, and natural medicinal chemist, also pointed out in the article "Research Progress of Ginsenoside R" (published in the issue of "Ginseng Research") that ginsenoside R, in addition to Ginsenosides have the function of improving immunity and have strong anti-cancer activity. Both in vivo and in vitro experiments have confirmed that ginsenoside R can inhibit the reproduction and growth of cancer cells. Its mechanism of action is considered to be the induction of redifferentiation.
At the same time, clinical medication has shown that ginsenoside R can resist the damage caused by radiotherapy and chemotherapy to peripheral blood cells, protect hematopoietic function and protect the gastric mucosa, improve gastrointestinal function, strengthen the patient's constitution, improve disease resistance, and reduce the chance of infection. Organs and reduce organ function damage. Thereby improving the quality of life and reducing pain of chemotherapy patients.
According to the existing experimental research literature, R can resist the adverse reactions of radiotherapy and chemotherapy in the following aspects.
. It can resist the damage caused by radiotherapy and chemotherapy to peripheral blood cells, and also has obvious protective and promoting effects on bone marrow hematopoietic function. Effectively prevents bone marrow damage during radiotherapy and chemotherapy, which is beneficial to the completion of radiotherapy and chemotherapy cycles and improves clinical efficacy.
. R is not only a tonic agent for tonic treatment, but also a protective agent for the functions of various organs and tissues, including the gastrointestinal tract. It can effectively protect the gastric mucosa, improve gastrointestinal function, increase appetite and food intake, and significantly Reduce gastrointestinal adverse reactions caused by radiotherapy and chemotherapy.
. R can increase the specific and non-specific immune functions of cancer patients. Enhance the patient's physical constitution, improve disease resistance, reduce the chance of infection, and increase the tolerance of the patient's tissues and organs to radiotherapy and chemotherapy.
. Protect organ function against damage to organ function caused by radiotherapy and chemotherapy.
In short, R has shown obvious efficacy in clinical and experimental studies in preventing and treating adverse reactions of radiotherapy and chemotherapy
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