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It is of great significance to choose an effective method and timely treatment for the recurrence of rectal cancer after surgery. The symptoms of postoperative recurrence of rectal cancer are often atypical and easy to ignore. This brings great difficulties to the treatment of postoperative recurrence of rectal cancer. According to literature reports, rectal cancer The local recurrence rate of cancer is .%~%, and about % of patients die from local recurrence without distant metastasis. Generally, if rectal cancer recurs, as long as the patient has no distant metastasis and the general condition is tolerable, reoperation should be considered first. If the age Patients who are large and in poor physical condition cannot tolerate surgery, radiotherapy and chemotherapy. Conservative treatment with traditional Chinese medicine can be used. It can control the development of the disease, improve the patient's quality of life, and extend the life span. Rectal cancer is a common malignant tumor in the gastrointestinal tract. , the incidence rate is second only to gastric and esophageal cancer, the vast majority of patients are over 10 years old, and about % are under 10 years old. It is more common in men, and the ratio of men to women is:. With the improvement of medical level, the treatment status of rectal cancer has been significantly improved compared with the past. However, the treatment status of late-stage rectal cancer is still not ideal. The treatment effect is related to the choice of treatment method and the patient's physical function. So, how to treat late-stage rectal cancer?
(1) Surgical treatment is divided into two types: radical and palliative.
The method of radical surgery depends on the location of the cancer in the rectum. There are two systems in the rectal wall: submucosal lymphatic plexus and myenteric lymphatic plexus. Metastasis of cancer cells in the lymphatic system in the intestinal wall is rare. Once cancer cells penetrate the intestinal wall, they spread to the lymphatic system outside the intestinal wall. Generally, the paraintestinal lymph nodes at the same level or slightly higher than the cancer are first involved, then gradually upward to involve the middle lymph node group accompanying the superior hemorrhoidal artery, and finally to the lymph node group next to the inferior mesenteric artery. The above-mentioned upward lymphatic metastasis is the most common metastasis mode of rectal cancer. If the cancer is located in the lower rectum, the cancer cells can also invade the obturator lymph nodes laterally along the lymphatic vessels of the levator ani muscle and pelvic wall fascia, or flow to the internal iliac lymph nodes along the middle hemorrhoidal artery.
Sometimes cancer cells can also pass downward through the levator ani muscle and drain along the inferior hemorrhoidal artery to the lymph nodes in the ischiorectal fossa and inguinal lymph nodes. Since the lymphatic metastasis direction of upper rectal cancer is almost always upward, surgical resection of the adjacent and inguinal lymph nodes of the cancer is Lymphatic tissue above this level can achieve radical cure, and surgery may preserve the anal sphincter. Although the lymphatic metastasis of lower rectal cancer is mainly upward, there is also the possibility of lateral metastasis to the internal iliac lymph nodes and obturator lymph nodes. Radical surgery needs to include the tissues around the rectum and anal canal and the levator ani muscle, so the anal sphincter cannot be preserved.
() Combined abdominoperineal resection (surgery): suitable for lower rectal cancer that is not far enough from the anal verge. The resection scope includes the sigmoid colon and its mesentery, rectum, anal canal, levator ani muscle, ischiorectal fossa tissue and The skin and blood vessels around the anus are ligated and cut below the root of the inferior mesenteric artery or the branch of the left colonic artery, and the corresponding paraarterial lymph nodes are cleaned. A permanent colostomy (artificial anus) is made in the abdomen, and the perineal wound is sutured or packed with gauze. This surgery is complete resection and has a high cure rate.
() Low abdominal resection and extraperitoneal primary anastomosis, also known as anterior resection of rectal cancer (n surgery), is suitable for upper rectal cancer above the anal verge and removes most of the sigmoid colon and rectum in the abdominal cavity. , free the rectum below the peritoneal reflection, and anastomose the sigmoid colon and rectum extraperitoneally. This surgery is less invasive and can preserve the original anus, which is ideal. If the cancer is large and has infiltrated surrounding tissue, it should not be used.
() Anal sphincter-preserving rectal cancer resection: suitable for early-stage rectal cancer ~ from the anal verge. If the cancer is large, poorly differentiated, or the main upward lymphatic vessels have been blocked by cancer cells and there is transverse lymphatic metastasis, this surgical approach will not be complete, and a combined abdominoperineal resection is better. The currently used methods of anal sphincter-preserving rectal cancer resection include stapler anastomosis, transabdominal low resection-transanal eversion anastomosis, transabdominal free resection-transanal pull-out resection anastomosis, and transabdominal transsacral resection. Select according to specific circumstances.
. Palliative surgery. If the local infiltration of the cancer is severe or the metastasis is extensive and cannot be cured, in order to relieve the obstruction and reduce the patient's pain, palliative resection can be performed. The intestinal segment with the cancer will be resected to a limited extent and the rectum will be sutured. The distal resection end is removed, and the sigmoid colon is taken as a stoma (rnn surgery). If this is not possible, only sigmoid colostomy is performed, especially in patients with intestinal obstruction.
Generally speaking, the only way to cure colon cancer is to remove the cancer through early surgery. However, after radical resection of colon cancer, about % of cases still experience recurrence and metastasis, mainly because occult metastases were not discovered before surgery or the lesions were not completely removed during surgery. Therefore, many colon cancer patients choose to take ginsenoside R in conjunction with surgical treatment. Taking ginsenoside R before surgery can shrink the tumor, reduce the scope of surgery, and improve the success rate of surgery; taking it after surgery can eliminate residual cancer cells, effectively prevent recurrence and metastasis, and at the same time accelerate incision healing, anti-inflammatory and analgesic, and prevent and treat infection. , prevent complications.
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