flumequin

Flumequine Chinese synonyms: Flumequine fluoride, dihydromethyl oxo, benzoquinazine carboxylate, flumequine flumequine sodium, flumequine powder
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Special antibacterial drugs for animals
Fluomequine, also known as fluoquinoic acid and fluroquinoic acid, is the second generation of synthetic Quinolone animal-specific antibacterial drugs are currently the only broad-spectrum antibacterial veterinary drugs that are not shared with humans. They are substitutes for norfloxacin. They have strong bactericidal activity and are very effective against bacterial diseases in animals. . Its main function is to inhibit the DNA gyrase of bacteria, interfering with the synthesis of DNA proteins, so that cells can no longer divide, thus playing a bactericidal effect. Mainly used for bacterial respiratory diseases of livestock and poultry, Escherichia coli, pullorum, salmonellosis, typhoid fever, fowl cholera, staphylococcal infectious rhinitis, etc. It has a strong inhibitory effect on colibacillosis, monospora and vibrio diseases of aquatic animals, and Aeromonas hydrophila.
Flomequine was first successfully developed in a laboratory and has been widely used in livestock, poultry and aquaculture in countries such as the European Union and Japan since the 1990s. It has very good effects on diseases caused by various Gram-negative bacterial infections. It has good curative effect, especially on livestock, poultry and aquatic animal diseases caused by Escherichia coli, Mycoplasma hydrophila and Aeromonas hydrophila. It was gradually developed and put on the market in our country in the late 1990s, and it is mainly used for the prevention and treatment of bacterial infectious diseases such as salmon, trout, shrimp, eel, pigs and chickens.
Because the quinolone antibacterial drug flumquine sodium can inhibit bacterial helicase, has a broad antibacterial spectrum, high efficiency, low toxicity, strong tissue penetration and no anesthetic effect, it has become one of the most important anti-infective drugs in veterinary clinics and aquaculture. 1. It is widely used for treatment, prevention and growth promotion. Due to its drug resistance and potential carcinogenicity, the European Union, Japan and my country have set maximum residue limits for their tissues. Both my country and the European Union have set maximum residue limits for their tissues. At present, the detection methods for flumequine mainly include fluorescence spectrophotometry, enzyme-linked method and liquid chromatography. It has become a routine screening method due to its high sensitivity and easy operation.
Usage: It is a new broad-spectrum antibacterial synthetic drug that has good curative effect on animal bacterial diseases. It is suitable for livestock and poultry, seawater, freshwater fish, shrimps and crabs.
Mechanism of action Flumequine achieves bactericidal effects by inhibiting the synthesis of bacterial nucleic acids and preventing bacterial replication. Mainly used for bacterial respiratory diseases of livestock and poultry, Escherichia coli, pullorum, salmonellosis, typhoid fever, fowl cholera, staphylococcal infectious rhinitis, etc. It has a strong inhibitory effect on colibacillosis, monospora and vibrio diseases of aquatic animals, and Aeromonas hydrophila.
Features The editing effect is good. In addition to killing general bacteria, it is especially effective against gastrointestinal and respiratory tract infections.
It is not easy to produce cross-drug resistance. Gram-negative bacteria are highly sensitive to this product. There is no cross-resistance with oxytetracycline, thiamphenicol, and erythromycin, but there is partial cross-resistance with quinolones.
The residue is small, and only one day of drug withdrawal is needed for pigs, and only one day for chickens and fish.
Wide safety range, no adverse reactions, no poisoning if doubled dosage. Oral administration of flumequine to river eel is above 1/kg per hour. The concentration of flumequine in bathed freshwater prawns was above mg/L. Tests on mice show that it is mg mg/kg. According to the general toxicity method and toxicity classification of new veterinary drugs of the Ministry of Agriculture, flumequine is of low toxicity and is safe for aquatic animals, livestock and poultry.
Absorption is good When flumquinequin is administered orally, the given dose is absorbed by the intestines, and the blood concentration reaches the peak within hours, and is excreted within hours, approximately excreted in urine and feces. After excretion, flumequin is absorbed into the body, the main metabolite is flumquine, which accounts for approximately, the hydroxylated metabolite.
Related products Flumequine sodium
The product is white crystalline powder, odorless
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Packing cardboard drum